Maintaining sufficient vitamin D levels may help to prevent the on-set of inflammatory diseases like rheumatoid arthritis, research led by the University of Birmingham has discovered. The research also found that while Vitamin D can be effective at preventing the on-set of inflammation, it’s less effective once inflammatory disease is established because diseases such as [...]
Treatment with biologics does not increase the risk of a second malignancy in rheumatoid arthritis (RA) patients who have a history of cancer, according to new research findings recently presented at the 2017 ACR / ARHP Annual Meeting. Biologic disease-modifying antirheumatic drugs, or biologics, are used to control rheumatoid arthritis disease activity and prevent joint [...]
Researchers have discovered a new marker of arthritis in mice that can be used non-invasively to both identify joints with established arthritis and to predict subsequent joint swelling. The finding is published in Arthritis & Rheumatology. The investigators note that imaging tests with the marker – called Ratiometric thrombin-Activatable Cell Penetrating Peptide – might help [...]
Those who treat patients suffering with severe asthma know how frustrating it can be to try to get the disease under control – despite the introduction in recent years of both biologics and bronchial thermoplasty. These treatments have proven effective, but require an understanding of all that is involved before being prescribed or recommended. An [...]
Scientists have made a fundamental discovery about how our body’s immune system clears harmful infections. Researchers have identified a previously unknown mechanism by which the responses of key cells of the immune system are regulated. The finding could inform research into improved treatments for allergies or chronic inflammatory diseases, such as lung and liver fibrosis, [...]
Several cutting-edge treatments have become available in recent years to correct the debilitating chronic lung congestion associated with cystic fibrosis (CF). While the new drugs are life-changing for some patients, they do not work for everyone. In a study published in the Journal of Clinical Investigation Insight, a team led by UNC researchers presented a [...]
A molecular smoke alert has now been developed by Dresden researchers for the TP53 gene, the most important human cancer gene. The alert goes on if the TP53 gene is mutated in cells. The molecular smoke detector works like a TP53 sensor, which monitors the correct function of the gene. A non-functional TP53 gene is [...]
In research published in the latest edition of the UEG Journal, scientists in Finland demonstrated that there’s variance in the volatile compounds found in the urine of pancreatic cancer patients to that of healthy controls. Research was then undertaken to assess whether Field Asymmetric Ion Mobility Spectrometry (FAIMS) technology could effectively differentiate between pancreatic cancer [...]
After years of rigorous research, a team of scientists has identified the genetic engine that drives a rare form of liver cancer. The findings offer prime targets for drugs to treat the usually lethal disease, fibrolamellar hepatocellular carcinoma (FL-HCC), which mainly strikes adolescents and young adults. Sanford Simon, who conducted the research as head of [...]
New treatments for dry eye disease that deliver lipids to the ocular surface are designed to more closely mimic the important tear film lipid layer at the air-water interface in the eye. The range and effectiveness of lipid-based products to treat dry eye disease, including liposome lid sprays, emulsion eye drops, lipid nanoparticles, and lipid-drug [...]
